| Start Date: | 10/25/2013 | Start Time: | 4:00 PM |
| End Date: | 10/25/2013 | End Time: | 5:30 PM |
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Event Description
Garth D. Ehrlich, PhD, professor of Microbiology & Immunology and Otolaryngology-Head & Neck Surgery, and executive director of both the Center for Genomic Sciences (CGS) and the Center for Advanced Microbial Processing (CAMP), Institute for Molecular Medicine and Infectious Disease (IMMID) and the Department at Microbiology and Immunology at Drexel College of Medicine, will discuss how the “Intelligent Implant” was conceptualized in 2003 as a medical device that could sense, report, and treat a bacterial infection without any input from the patient or the physician. Such a device would therefore be required to have a chemical means of bacterial detection, a self-contained power supply, a reservoir for antimicrobial compounds, a means to release the antibiotics upon sensing an infection, and a wireless means for communication with the outside world. The molecular sensing mechanism and the reservoir release were considered the two greatest challenges. These challenges were further magnified by the desirability of being able to “reset” the system after triggering for future (or multiple) microbial events. For the chemical sensing of the bacteria we chose as a first target to have the device “listen in” on the bacterial communication system termed, quorum sensing. This was to be accomplished through the design of a MEMS device that would transduce a molecular binding signal to a viscosity-based cantilever system which would, in turn, trigger the release of the reservoir contents.
For more info, please visit www.biomed.drexel.edu |
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Location:
Bossone Research Enterprise Center, Mitchell Auditorium (Bossone is located at the corner of 32nd and Market Streets). |
Audience:
AlumniCurrent StudentsFacultyProspective StudentsPublicStaff |
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