| Start Date: | 11/22/2013 | Start Time: | 4:00 PM |
| End Date: | 11/22/2013 | End Time: | 5:30 PM |
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Event Description
Elisabeth Van Bockstaele, PhD, Founding Dean of the Graduate School of Biomedical Sciences and Professional Studies, Drexel University College of Medicine, will discuss how anxiety disorders comprise a group of psychiatric illnesses that are among the most common mental health conditions. The noradrenergic system continues to be an important target in the development of new therapies because of its critical role in the modulation of emotional state and regulation of arousal and stress responses. In addition, the use of synthetic cannabinoid receptor agonists/antagonists or compounds targeting endocannabinoid synthesis/metabolism in brain has received widespread attention as these approaches may hold some therapeutic potential for psychiatric disorders. Dr. Bockstaele’s and her team's research has highlighted significant interactions between cannabinoids and the noradrenergic system in cortical and limbic brain regions. She and her team provided evidence that, under basal conditions, exposure to a synthetic cannabinoid receptor agonist increases anxiety-like behaviors that correlate with increases in multiple indices of brain noradrenergic activity. New findings indicate a different consequence to the regulation of norepinephrine by cannabinoids, under conditions of stress. These data suggest complex actions of cannabinoids on noradrenergic circuitry that vary under basal vs stress conditions. Targeting interactions between these two systems may provide novel therapies for the treatment of stress-induced anxiety disorders. For more info, please visit: www.biomed.drexel.edu |
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Location:
Bossone Research Enterprise Center, Mitchell Auditorium (Bossone is located at the corner of 32nd and Market Streets). |
Audience:
AlumniCurrent StudentsFacultyProspective StudentsPublicStaff |
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