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Aerodynamic Principles Applied to Coronary Stent Design
Start Date: 2/13/2015Start Time: 4:00 PM
End Date: 2/13/2015End Time: 5:30 PM
Event Description
Juan M. Jiménez, PhD, research associate in the department of pathology and laboratory medicine in the Perelman School of Medicine, University of Pennsylvania, will discuss how cardiovascular disease is the number one cause of death throughout the world (WHO). The most common type is coronary heart disease and stenting has become one of the preferred therapies for treatment. Stents, small cylindrical meshes that get implanted at the site of an obstructed cardiac vessel, allow re-establishment of blood flow to the heart. In the USA alone about 650,000 stents are implanted yearly, predominantly drug eluting stents (DES), which elute drugs to arrest the migration and proliferation of cells that could re-close the vessel (restenosis). However, the topography of a "healed vessel" may be characterized by protruding, uncovered stent struts or struts covered by a thin layer of acellular material causing blood flow perturbations. Both experimentally and numerically, we have demonstrated that nonstreamlined stent strut geometries similar to commercial stents can create a local fluid flow environment conducive toward the development of pro-coagulant (pro-thrombotic) conditions. For more info, please visit www.biomed.drexel.edu
Contact Information:
Name: Ken Barbee
Phone: 215-895-1335
Email: barbee@drexel.edu
Biomed DEC.jpg
Location:
Papadakis Integrated Sciences Building (PISB), Room 120, located at the corner of 33rd and Chestnut Streets.
Audience:
  • Undergraduate Students
  • Graduate Students
  • Faculty
  • Staff
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