| Start Date: | 2/12/2016 | Start Time: | 4:00 PM |
| End Date: | 2/12/2016 | End Time: | 5:30 PM |
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Event Description
Event Description
BIOMED Seminar
Title:
Quantifying Age- and Gender-specific Variations in the Pediatric Spine and Rib Cage Morphology to Develop Patient-Specific Computational Models for Scoliosis Treatment
Speaker:
Sriram Balasubramanian, PhD
Assistant Professor
School of Biomedical Engineering, Science & Health Systems
Drexel University
Details:
Scoliosis is a three-dimensional (3D) progressive deformity of the spine and ribcage that affects five to nine million individuals in the United States. 65% of these cases are Adolescent Idiopathic Scoliosis (AIS) in children ages 10-18 years. AIS is more than 10 times more common in girls than in boys, with an overall ratio of 11:1. The rate of progression also varies greatly with the type and severity of the deformity.
Though spinal fusion is the most common intervention to correct AIS deformity, this method limits the patient's future growth. Knowledge of the growth remaining in the spine and rib cage is critical for predicting progression and surgical planning. There is limited literature on the 3D structure and growth of the normative pediatric spine and rib cage. There is also very limited and conflicting literature on the sequelae of structural and positional changes in the ribs and vertebral morphology with varying severities of AIS. The objectives of this study are to (1) quantify the age- and gender-related changes in normative pediatric spine and rib cage morphology and growth, (2) study the pathoanatomy of the vertebrae and rib hump in AIS subjects with varying curve-types, and (3) develop AIS patient-specific finite-element (FE) models of the spine and rib cage.
Our FE models will incorporate growth in the scoliotic spine, allowing clinicians to better understand deformity progression. Such advanced models will aid in determining the effectiveness of deformity-specific interventions, and with preoperative planning to aid in the prescription for AIS patient-specific correction.
For more info, please visit drexel.edu/biomed.
WATCH WEBCAST
Biosketch:
Dr. Sriram Balasubramanian, PhD is an Assistant Professor in the School of Biomedical Engineering, Science and Health Systems at Drexel University. Dr. Balasubramanian also serves as an Assistant Professor in the Department of Orthopedic Surgery at Drexel University College of Medicine and is an Adjunct Senior Research Scientist at the Center for Injury Research and Prevention at The Children’s Hospital of Philadelphia (CHOP).
As the director of the Orthopedic Biomechanics Laboratory at Drexel University, Dr. Balasubramanian’s research is focused on developing novel biomedical engineering methods and advanced computational modeling tools to address the burden of debilitating pediatric skeletal deformities, traumatic injuries and orthopedic conditions. He specializes in characterizing the morphology and growth patterns of the normative and scoliotic pediatric spine and rib cage, rapidly creating patient-specific computational models to simulate surgical interventions, and developing age-equivalent animal models for scoliosis and pediatric long bones.
Dr. Balasubramanian’s research expertise also includes experimental biomechanics in the areas of pediatric head and neck injury, orthopedic biomechanics of the knee, thorax and spine, and knee biomechanics following ligament reconstructions. He has conducted several human volunteer studies, sled tests with postmortem human subjects and experimental studies using cadaveric tissue.
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Location:
Papadakis Integrated Sciences Building (PISB), Room 120, located on the northeast corner of 33rd and Chestnut Streets. |
Audience:
Undergraduate StudentsGraduate StudentsFacultyStaff |
Special Features:
Online Access |
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