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Decision Making, Event-Related Potential and Non-Cholinergic Basal Forebrain Neurons
Start Date: 2/15/2013Start Time: 4:00 PM
End Date: 2/15/2013End Time: 5:30 PM
Event Description
Dr. Shih-Chieh Lin, investigator in the Neural Circuits and Cognition Unit of the Laboratory of Behavioral Neuroscience at the National Institute on Aging / NIH, will discuss how basal forebrain (BF) is an important structure implicated in attention, arousal, and the control of cortical activity and plasticity. Studies in Dr. Lin's laboratory are guided by the hypothesis that cortically projecting GABAergic BF neurons encode the motivational salience of attended stimuli and translate this salience signal into fast and widespread amplification of cortical activity, resulting in enhanced behavioral performance. In this talk, Dr. Lin will describe new data from his team's ongoing studies linking non-cholinergic BF neurons to the generation of an event-related potential (ERP) response in the frontal cortex, and how these BF neurons regulate the speed and variability of a decision making process. These results establish the functional significance of the often-neglected non-cholinergic BF neurons.
Contact Information:
Name: Banu Onaral
Phone: 215-895-2247
Email: banu.onaral@drexel.edu
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Location:
The Papadakis Integrated Sciences Building, located on the northeast corner of 33rd and Chestnut Streets.
Audience:
  • Alumni
  • Current Students
  • Faculty
  • Prospective Students
  • Public
  • Staff
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