Event Description
Presenter
Siddharth Vyas
Title
Modeling Magnetic Separation for Novel Applications in Medicine and Biology
Advisor
Drs. Gary Friedman and Vladimir Genis
Abstract
The proposed research seeks to qualitatively and quantitatively understand the mechanism of separation of magnetic particles in two specific High Gradient Magnetic Separation based systems of Magnetic Drug Targeting and Magnetic Diagnosis of Malaria. A quasi-analytical model is developed to understand the mechanism of separation by observing the trajectory of magnetic particles in these systems for varying conditions.
For magnetic stent-assisted drug targeting systems, the aim of the model is to help understand the mechanism of capture of drug-carrying magnetic particles by magnetic stent wires by studying the influence of orientation of stent magnetization on the trajectory of magnetic particles that are in the flow. The model will also study the distribution of captured particles across the stent wire. So far, there are no convincing theoretical studies in these areas.
For magnetically diagnosing malaria, the aim of the model is to assist in the design of a system that is capable of separating malaria-infected red blood cells from healthy red blood cells for diagnosis and evaluation of malaria. Because malaria is more prevalent in poorer parts of the world where there is a lack of equipment and trained personnel, the focus will be to achieve a design that is inexpensive and easy to use. |
