| Start Date: | 4/1/2016 | Start Time: | 4:00 PM |
| End Date: | 4/1/2016 | End Time: | 5:30 PM |
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Event Description
BIOMED Seminar
Title:
Microfabricated Medical Devices for Diagnostics and Advanced Biological and Cellular Manipulations: From Neural Probes to Electroporation
Speaker:
Jeffrey D. Zahn, PhD
Associate Professor
Department of Biomedical Engineering
Rutgers University
Details:
The focus of research conducted in the Zahn laboratory is the design and fabrication of microfabricated devices for clinical diagnosis, treatment of disease and supportive culture devices. Batch fabricated microfluidic platforms that can mimic or improve upon conventional sample preparation techniques performed in laboratories hold great potential to enable both research and healthcare advances. These miniaturized diagnostic devices have been termed micro total analysis systems (μTAS) or biochips and combine sensing mechanisms (physical, optical, electrical or chemical) with microfluidics. While microfluidics promises to have an impact in many research fields, one of the more attractive applications has been towards biomedical and life science diagnostics. There is a growing market for point of care diagnostic devices for both bedside and outpatient monitoring.
Dr. Zahn’s research combines analytical and numerical modeling of microscale phenomena with device design, fabrication, and testing of microfluidic components in an adaptive and iterative process for device optimization. Several projects currently underway in the Zahn laboratory which will be discussed include:
- using microfluidic technologies for patient monitoring during extracorporeal support (hemodialysis, cardiopulmonary bypass and extracorporeal life support). These use a specially designed microfiltration device which allows continuous blood plasma filtration followed by a device which automates the serial incubation steps required using paramagnetic core immunofluorocytometry beads for continuous biomarker monitoring during support,
- the development of ultra-miniaturized cortical recording probes which limit gliosis permitting better long term integration with neural tissue to improve performance for brain computer interface signal acquisition,
- devices supporting neuronal mini-circuitry models to evaluate connectivity or study response to injury, and
- developing a ‘smart’ electroporator which automates single cell detection and applies an electroporation pulse with continuous cell impedance monitoring in order to improve cell viability while optimizing molecular delivery.
For more info, please visit drexel.edu/biomed.
WATCH WEBCAST
Biosketch:
Jeffrey D. Zahn is an associate professor of Biomedical Engineering at Rutgers, The State University of New Jersey. He graduated from the Joint UCSF-UC Berkeley Graduate Group in Bioengineering in 2001. He graduated from the Massachusetts Institute of Technology, in 1995, with a Bachelor of Science degree in Chemical Engineering and a minor in Biology. He has been supported by the NIH, NSF, and ADA as well as the Wallace H. Coulter Foundation Early Career Translational Research in Biomedical Engineering award.
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Location:
Papadakis Integrated Sciences Building (PISB), Room 120, located on the northeast corner of 33rd and Chestnut Streets. |
Audience:
Undergraduate StudentsGraduate StudentsFacultyStaff |
Special Features:
Online Access |
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