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Cyclic Stretch Induced Oxidative Injury Increases Alveolar Permeability via ERK-NF-kB Signaling
Start Date: 5/18/2012Start Time: 4:00 PM
End Date: 5/18/2012End Time: 5:30 PM

Event Description
Dr. Davidovich, postdoctoral researcher at the University of Pennsylvania, will discuss how mechanical ventilation with high tidal volumes has been associated with pulmonary alveolar flooding and how understanding the mechanisms underlying cyclic stretch-induced increases in alveolar epithelial permeability may be important in designing preventive measures for acute lung injury. His work seeks to assess whether cyclic stretch leads to the generation of reactive oxygen species, which in turn increase type I epithelial cell monolayer permeability via activation of nuclear factor-kappaB (NF-kB) and extracellular signal-regulated kinase (ERK). For more info, please visit: www.biomed.drexel.edu.
Contact Information:
Name: Banu Onaral
Phone: 215-895-2247
Email: banu.onaral@drexel.edu
biomed_logo_name_DEC.jpg
Location:
The Papadakis Integrated Sciences Building (located at the northeast corner of 33rd and Chestnut Streets).
Audience:
  • Alumni
  • Current Students
  • Faculty
  • Prospective Students
  • Public
  • Staff
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