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Physics Colloquium: Advances in Hyperpolarized Magnetic Resonance
Start Date: 11/11/2021Start Time: 3:30 PM
End Date: 11/11/2021End Time: 4:30 PM
Event Description
Nicholas Whiting
Rowan University

While magnetic resonance techniques are versatile in their ability to perform high resolution, non-destructive chemical spectroscopy (NMR) and medical imaging (MRI), they suffer from a fundamental lack of detection sensitivity. To combat this, we highlight the use of three hyperpolarization techniques that provide orders-of-magnitude enhancement of nuclear spin polarization. This includes using spin-exchange optical pumping to produce gas-phase MRI contrast agents (e.g., 129Xe) for pulmonary imaging. The second approach utilizes dynamic nuclear polarization to create long-lived MR signal amplification in silicon- and carbon-based nanomaterials, with a goal of their development as targeted molecular imaging agents. Finally, we’ll discuss recent advances in the production and characterization of low-cost parahydrogen gas, which can enhance X-nuclei on other molecules of interest. This collection of techniques has demonstrated an ability to boost MR signals for a diversity of samples, and their continued development will better-allow for the detection of dilute samples, studies with high temporal resolution, and MR at lower magnetic fields.  
Contact Information:
Name: Professor Goran Karapetrov
Phone: 215-571-4090
Email: gk327@drexel.edu
Location:
Drexel University
Department of Physics
Audience:
  • Undergraduate Students
  • Graduate Students
  • Faculty
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