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Diffusion MRI in Ultra-high Field
Start Date: 5/1/2019Start Time: 4:00 PM
End Date: 5/1/2019End Time: 5:30 PM
Event Description
BIOMED Seminar

Diffusion MRI in Ultra-high Field

Hao Huang, PhD 
Research Associate Professor, Department of Radiology 
Faculty Director, Small Animal Imaging Facility 
Children’s Hospital of Philadelphia 
Perelman School of Medicine 
University of Pennsylvania

The volume of a mouse brain is approximately 3, 000 times smaller than that of a human brain. Revealing anatomical details of the small animal brain requires higher resolution (e.g., 0.1-0.2mm isotropic). Ultra-high field (UHF) (e.g., 7.0 Tesla, 9.4 Tesla, 11.7 Tesla, or even 17 Tesla) for magnetic resonance imaging (MRI) is needed for sufficient signal-to-noise ratio (SNR) of animal diffusion MR images. The audience will understand current technical challenges and possible solutions of animal diffusion imaging at UHF. 

Several applications of animal diffusion imaging at UHF will be introduced. These applications include delineation of mouse embryo anatomical structures with high contrasts of diffusion tensor microimaging, microstructural measurement of animal brain cerebral cortex and white matter tracts, tractography of mouse brain white matter tracts, establishment of animal brain atlases and biomarker detection with diffusion MRI of animal model.

Hao Huang, PhD, is an internationally recognized leader in pediatric neural magnetic resonance imaging (MRI). He is known best for imaging brain development and has been interviewed by Science and Nature Medicine on this topic. 

Dr. Huang is on the Editorial Board of NeuroImage, a top journal in the neuroimaging field. He has published nearly 100 peer-reviewed articles in journals such as Nature, PNAS, Trends in Neurosciences, Molecular Psychiatry, Journal of Neuroscience, Cerebral Cortex and Annals of Neurology. Dr. Huang maintains a strong NIH funding track-record and supports a laboratory of 10 members.

Contact Information:
Name: Ken Barbee
Phone: 215-895-1335
Hao Huang
Papadakis Integrated Sciences Building (PISB), Room 120, located on the northeast corner of 33rd and Chestnut Streets.
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