| Start Date: | 11/7/2016 | Start Time: | 10:00 PM |
| End Date: | 11/8/2016 | End Time: | 12:00 AM |
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Event Description
BIOMED PhD Research Proposal (1st SJTU-DU Dual PhD)
Speaker:
Lin Cheng, Dual PhD Candidate, School of Biomedical Engineering, Science and Health Systems and Shanghai Jiao Tong University (SJTU)
Advisors:
Hasan Ayaz, PhD, Associate Research Professor, School of Biomedical Engineering, Science and Health Systems
Shanbao Tong, PhD, Professor, Shanghai Jiao Tong University (SJTU)
Junfeng Sun, PhD, Professor, Shanghai Jiao Tong University (SJTU)
Title:
Dynamic Adaptation of Brain Networks from Rest to Task and Application to Neurorehabilitation
Abstract:
Examining how motor tasks would modulate brain activity plays a critical role in understanding the brain networks and the development of new approaches for rehabilitation of disabilities induced by neurological diseases, such as stroke. Recent advances in neuroimaging, such as functional Magnetic Resonance Imaging (fMRI) and functional Near Infrared Spectroscopy (fNIRS), have resulted in numerous studies focusing on motor-induced modulation of brain activity. The most widely used strategy of these studies involved finding activated brain regions during tasks via event-related/block-design experiment paradigms. Despite progress obtained, motor-related activation analysis mainly focused on modulation of brain activities for individual brain regions. However, the brain has been demonstrated to consist of discrete, large-scale networks with widely spaced nodal regions, which show highly correlated activity across time, and such correlation is interpreted as functional connectivity. Thus, in addition to the motor-related activation, an understanding of how the brain networks, especially its motor networks, reorganizes spatiotemporally in response to the motor tasks based on fMRI and fNIRS and is critical for revealing the underlying adaptation within the brain in regards to motor tasks. This could be applied to the research of motor disability induced by neurological diseases.
The three specific aims of this thesis are: 1) Reveal how the brain network reorganizes from rest to motor preparation, as well as motor execution; 2) Examine the dynamic spatiotemporal reorganization of motor network, as well as high-level cognitive brain networks from rest to motor tasks; 3) Assess the relationship of motor-state brain networks with function restoration of motor disability induced by stroke. |
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Location:
Med-X Building, Room 218, Shanghai Jiao Tong University (SJTU), Shanghai, China |
Audience:
Undergraduate StudentsGraduate StudentsFacultyStaff |
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