| Start Date: | 11/9/2016 | Start Time: | 4:00 PM |
| End Date: | 11/9/2016 | End Time: | 5:30 PM |
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Event Description
BIOMED Seminar
Title:
Engineering Technologies for Preclinical Osteoarthritis (OA) Research
Speaker:
Kyle D. Allen, PhD
Assistant Professor and Associate Chair for Undergraduate Studies
J. Crayton Pruitt Family Department of Biomedical Engineering
University of Florida
Abstract:
Osteoarthritis (OA) is a non-life-threatening, but incurable, disease that ultimately results in chronic pain and disability. However, OA pain and disability is a complex phenomenon, as the severity of joint degeneration in OA patients does not necessarily correlate to the severity of symptoms. Moreover, animal models of acute joint pain may not fully replicate chronic pain mechanisms in OA. Unfortunately, the current reality for OA drug development is that safety and efficacy will need to be tested in a preclinical model prior to clinical testing. Thus, the lack of unifying relationships between OA pathogenesis and symptoms remains a significant obstacle to the development and translation of OA therapies.
To improve the translation and development of OA therapeutics, our ability to investigate preclinical OA models must become more relevant to OA treatment in the clinic. This challenge is the central motivator for the Orthopedic Biomedical Engineering Laboratory at the University of Florida research program, where we are developing engineering technologies to improve the preclinical-to-clinical translation of emerging OA diagnostics and therapeutics, including behavioral assays of symptomology in rodent preclinical models and magnetic nanoparticle technologies to assess joint-level molecular changes. These technologies can impact the preclinical evaluation of OA interventions, the development of novel diagnostics and disease modifying drugs, and the creation of new biological therapies for OA.
For more info, please visit drexel.edu/biomed.
WATCH WEBCAST
Biosketch:
Dr. Kyle Allen is an Assistant Professor and Associate Chair for Undergraduate Programs at the University of Florida. He is a previous winner of the K99/R00 Pathways to Independence Award and an F32 Ruth L. Kirschstein National Research Service Award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH/NIAMS). He has also been serving the Osteoarthritis Research Society International (OARSI) as Chair of the Young Investigator Subcommittee for the past year.
Since 2011, Dr. Allen has been leading the Orthopedic Biomedical Engineering Laboratory at the University of Florida, where his research program focuses on developing technologies for rodent models of joint disease. His laboratory is currently supported by funding from NIH/NIAMS. |
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Location:
Papadakis Integrated Sciences Building (PISB), Room 120, located on the northeast corner of 33rd and Chestnut Streets. |
Audience:
Undergraduate StudentsGraduate StudentsFacultyStaff |
Special Features:
Online Access |
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