Event Description
Topic
Microbes & Alzheimer’s: Bridging Silos to Accelerate Innovation
Agenda:
8:00 – 9:00am Breakfast
9:00 – 10:45am Presentations
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Dr. Brian Balin, Nikki Schultek, IDSA Opening remarks
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Nikki Schultek, AlzPI “Unraveling the role of infections in Alzheimer’s through
patient-led, global interdisciplinary collaboration”
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Dr. Brian Balin, PCOM & AlzPI "Evaluating infection in Alzheimer disease pathogenesis”
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Dr. Garth Ehrlich and Dr. Michiko Thwe, Drexel “Application of a species-specific, trans-pan-domain molecular diagnostic to Alzheimer disease (AD) brains reveals AD pathobiomes that are distinct from agematched
controls.”
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Dr. David Corry and Lynn Bimler, Baylor “A ubiquitous Candida albicans-based polymicrobial
human brain infection causes Alzheimer’s Disease-like changes in mice”
10:45 – 11am Questions & Break
11am – 12:20pm Presentations
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Dr. Kevin Zwezdaryk and
Sara Morris, Tulane “Intermittent CMV infection promotes mitochondrial
dysfunction contributing to Alzheimer’s Disease
progression”
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Nikki Schultek, AlzPI “Unraveling the role of infections in Alzheimer’s through
patient-led, global interdisciplinary collaboration”
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Dr. Elizabeth Bradshaw and Dr. Zena Chatila, Columbia “Pathogens, Microglia and Alzheimer’s Disease”
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Dr. Edward Breitschwerdt
and Dr. Janice Bush, NC State “Bartonella henselae, Neurobartonellosis and Alzheimer’ Disease: Is there a link?”
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Dr. Or Shemesh and
Vanesa Hyde, B.A., Univ. of Pittsburgh “Alzheimer’s Disease pathologies are pathogen-driven
and cell protective”
12:20 – 1:15pm Lunch
1:15 – 3:05pm Presentations
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*Keynote* Dr. Wenyuan Shi, Forsyth Institute “Exploring the connection between oral microbiome and Alzheimer’s disease ”
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Dr. Ruth Itzhaki, Oxford “Repetitive concussive injury, like cumulative infections, causes Alzheimer’s disease-like phenotypes via
reactivation of HSV-1 in a 3D human brain tissue model”
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Dr. William Eimer, MGH and Harvard “Amyloid Beta and Tau: Exploring the antimicrobial
connection between pathogens and Alzheimer’s
disease”
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Dr. Laura Cox, Harvard “The role of Bacteroides in Alzheimer’s disease. ”
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Dr. Monica Embers, Tulane “Borrelia Infection in the Genesis of Dementia”
3:05 – 3:20pm Questions & Break
3:20 – 3:40pm Presentations
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Dr. Lavinia Alberi, VitalizeDx and AlzPI “Oral-host pathogen interactions, from early noninvasive
diagnostics to timely therapeutics for
Alzheimer’s Disease”
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Dr. Michael Detke,
Lighthouse Therapeutics “Phase 1 SAD/MAD data and Phase 2 study design for
LHP588, a
second-generation gingipain inhibitor for the treatment
of P. gingivalis-positive Alzheimer’s dementia”
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*Keynote* Col. Nicole
Malachowski (ret.), USAF “Breaking Barriers”
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Dr. Laura Cox, Harvard “The role of Bacteroides in Alzheimer’s disease. ”
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Dr. Brian Balin, Dr. Ruth Itzhaki, & Dr. George Perry Pioneer’s Panel Discussion
5 – 7pm Cocktail Hour & Networking in the Lobby
Register Here
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