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Understanding the Benefit-Risk Calculus of Digital Health Interventions
Start Date: 10/26/2022Start Time: 4:00 PM
End Date: 10/26/2022End Time: 5:30 PM

Event Description
BIOMED Seminar


Understanding the Benefit-Risk Calculus of Digital Health Interventions

Eric D. Perakslis, PhD, MS
Chief Science and Digital Officer
Duke Clinical Research Institute
Professor, Department of Population Health Sciences
Duke University School of Medicine

Digital health represents one of the fastest growing sectors of healthcare. From internet-connected wearable sensors to diagnostics tests and disease treatments, it is often touted as the revolution set to solve the imperfections in healthcare delivery worldwide. While the health value of digital health technology includes greater convenience, more personalized treatments, and more accurate data capture of fitness and wellness, these devices also carry the concurrent risks of technological crime and abuses pervasive to cyber space. Even today, the medical world has been slow to respond to these emerging risks, despite the growing permanence of digital health technology within daily medical practice.

The short- and long-term success of digital health interventions will be dependent upon the ability to clearly quantify and articulate the corresponding benefits and risks. This is never easy as technology innovators are very good at identifying, and hyping, the potential benefits of their innovations but side effects can take years to manifest, resulting in rearward-facing regulation and inadequate risk determination. But the hazards of the internet are well known, and the benefit-risk calculus can be clear.

In this seminar we will examine the benefit-risk calculus of the digital health ecosystem with an eye towards quantitative balance and smart, proactive regulation that seeks not only to decrease risk, but to increase benefits, as well.
Eric Perakslis, PhD, is the Chief Science and Digital Officer at the Duke Clinical Research Institute & Professor of Population Health Sciences at the Duke University School of Medicine.
Prior to his appointment, Eric was a Rubenstein Fellow at Duke University, focused on collaborative efforts spanning medicine, policy, engineering, information technology and security. Immediately prior to his arrival at Duke, Eric served as CSO at Datavant, Lecturer in the Department of Biomedical Informatics at Harvard Medical School, and Strategic Innovation Advisor to Médecins Sans Frontières.

Eric was a Senior Vice President and Head of the Takeda R&D Data Science Institute, where he built an integrated institute serving all aspects of biopharmaceutical R&D and digital health. Prior to Takeda, Eric was the Executive Director of the Center for Biomedical Informatics and the Countway Library of Medicine, an Instructor in Pediatrics at Harvard Medical School, and a faculty member at the Children’s Hospital Informatics Program at Boston Children’s Hospital.

Eric has served as Chief Information Officer and Chief Scientist (Informatics) at the U.S. Food and Drug Administration. During his time at the FDA, he authored the first IT Strategic Plan and was responsible for modernizing, enhancing the IT capabilities and in silico scientific capabilities.

Prior to Eric’s FDA role, he was Senior Vice President of R&D Information Technology at Johnson & Johnson Pharmaceuticals R&D and a member of the Corporate Office of Science & Technology. While at J&J, he created and open-sourced the tranSMART clinical data system, which is now being freely used by hundreds of healthcare organizations. During his 13 years at J&J, Eric also held the posts of VP R&D Informatics, Director of Research Information Technology and Director of Drug Discovery Research.
Contact Information:
Name: Lisa Williams
Email: ltw22@drexel.edu
Eric Perakslis
Remote via Zoom
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